AffiAB® Anti-PDE2A Antibody
Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Plays an important role in growth and invasion of malignant melanoma cells (e.g. pseudomyxoma peritonei (PMP) cell line) .
Antibody type
Rabbit polyclonal Antibody
Uniprot ID
SwissProt: O00408 Human; SwissProt: Q922S4 Mouse
Recombinant
NO
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
N/A
KO/KD
N/A
Species reactivity
Human, Mouse
Tested applications
WB
Predicted species reactivity
N/A
Immunogen
Recombinant protein within human PDE2A aa 750-941.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
cGMP-PKG signaling pathway
Recommended dilutions
WB: 1:500-1:1, 000
Molecular Weight
Predicted band size:105 kDa.
Subcellular location
Cell membrane, Cytoplasm, Membrane, Mitochondrion, Mitochondrion inner membrane, Mitochondrion outer membrane.
Positive control
Human brainl tissue lysate, mouse lymphatic tissue lysate.