AffiAB® Anti-P2X3 Antibody
This gene encodes a member of the P2X purinergic receptor (purinoceptor) gene family which includes seven members (P2RX1 - P2RX7) . P2X purinoceptors are a family of cation-permeable, ligand-gated ion channels that open in response to the binding of extracellular adenosine 5'-triphosphate (ATP) . The encoded protein is a subunit of the trimeric P2X3 receptor ion channel which is expressed by sensory or autonomic neurons. A deficiency of the orthologous protein in mice is associated with reduced pain-related behavior and urinary bladder hyporeflexia.
Antibody type
Rabbit polyclonal Antibody
Uniprot ID
SwissProt: P56373 Human; SwissProt: Q3UR32 Mouse; SwissProt: P49654 Rat
Recombinant
NO
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
N/A
KO/KD
N/A
Species reactivity
Human, Mouse, Rat
Tested applications
WB, IHC-P
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within mouse P2X3 aa 348-397 / 397.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*PBS (pH7.4) , 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Immunogen affinity purified.
Signal pathway
Calcium signaling pathway
Recommended dilutions
WB:1:500-1:1, 000
; IHC-P:1:50-1:200
Molecular Weight
Predicted band size: 44 kDa
Subcellular location
Cell membrane.
Positive control
Mouse testis tissue lysates, rat spinal cord tissue, mouse brain tissue.