![AffiAB® Anti-OS9 Antibody [JG38-07]](/web/image/product.product/77294/image_1024/%5BAFG-HB-2805%5D%20AffiAB%C2%AE%20Anti-OS9%20Antibody%20%5BJG38-07%5D%20?unique=a48b62f)
AffiAB® Anti-OS9 Antibody [JG38-07]
Protein OS-9 is a protein that in humans is encoded by the OS9 gene.This gene encodes a protein that is highly expressed in osteosarcomas. This protein binds to the hypoxia-inducible factor 1 (HIF-1) , a key regulator of the hypoxic response and angiogenesis, and promotes the degradation of one of its subunits. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: Q13438 Human; SwissProt: Q8K2C7 Mouse; SwissProt: Q5RKH6 Rat
Recombinant
YES
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
JG38-07
KO/KD
N/A
Species reactivity
Human, Mouse, Rat
Tested applications
WB, IHC-P, IP
Predicted species reactivity
N/A
Immunogen
Recombinant protein within Human OS9 aa 561-667 / 667.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:500-1:2, 000
; IHC-P: 1:50-1:200
; IP: 1:10-1:50
Molecular Weight
76 kDa
Subcellular location
Endoplasmic reticulum.
Positive control
Mouse testis tissue lysate, rat testis tissue lysate, rat epididymis tissue, human breast carcinoma tissue, human placenta tissue, mouse testis tissue.