AffiAB® Anti-OC-3 Antibody
ONECUT3 (One Cut Homeobox 3) is a Protein Coding gene. Diseases associated with ONECUT3 include Dracunculiasis. Among its related pathways are Regulation of beta-cell development and Developmental Biology. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity and RNA polymerase II regulatory region sequence-specific DNA binding. An important paralog of this gene is ONECUT2. Transcriptional activator. Binds the consensus DNA sequence 5'-DHWATTGAYTWWD-3' on a variety of gene promoters such as those of HNF3B and TTR.
Antibody type
Rabbit polyclonal Antibody
Uniprot ID
SwissProt: O60422 Human
Recombinant
NO
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
N/A
KO/KD
N/A
Species reactivity
Human
Tested applications
WB, IHC-P, FC
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within human ONECUT3 aa 430-470.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Immunogen affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:500
; IHC-P: 1:100-1:500
; FC: 1:50-1:100
Molecular Weight
50 kDa
Subcellular location
Nucleus.
Positive control
SW480 cell lysate, Hela cell lysate, human stomach tissue lysate, AGS cell lysate, human colon carcinoma tissue, human stomach tissue, SW620.