![AffiAB® Anti-Nucleostemin Antibody [JG37-82]](/web/image/product.product/77254/image_1024/%5BAFG-HB-2763%5D%20AffiAB%C2%AE%20Anti-Nucleostemin%20Antibody%20%5BJG37-82%5D%20?unique=a48b62f)
AffiAB® Anti-Nucleostemin Antibody [JG37-82]
The protein encoded by this gene may interact with p53 and may be involved in tumorigenesis. The encoded protein also appears to be important for stem cell proliferation. Stabilizes MDM2 by preventing its ubiquitination, and hence proteasomal degradation. This protein is found in both the nucleus and nucleolus. Three transcript variants encoding two different isoforms have been found for this gene.
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: Q9BVP2 Human
Recombinant
YES
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
JG37-82
KO/KD
N/A
Species reactivity
Human
Tested applications
WB, IF-Cell, IHC-P, FC
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within C-terminal Human Nucleostemin .
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:500; IF-Cell: 1:50-1:200; IHC-P: 1:50-1:200; FC: 1:50-1:100
Molecular Weight
Predicted band size: 62 kDa
Subcellular location
Nucleus.
Positive control
A549 cell lysates, A549, HepG2, human lung cancer tissue, human breast cancer tissue, human skin tissue, human colon carcinoma tissue.