AffiAB® Anti-NSUN4 Antibody [4G3]

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CAT# AFG-HB-2752
Size: 100 μL

465.00 465.0 USD 465.00

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AffiAB® Anti-NSUN4 Antibody [4G3]

Involved in mitochondrial ribosome assembly. 5-methylcytosine rRNA methyltransferase that probably is involved in mitochondrial ribosome small subunit (SSU) maturation by methylation of mitochondrial 12S rRNA; the function is independent of MTERFD2/MTERF4 and assembled mitochondrial ribosome large subunit (LSU) . Targeted to LSU by MTERFD2/MTERF4 and probably is involved in a final step in ribosome biogenesis to ensure that SSU and LSU are assembled. In vitro can methylate 16S rRNA of the LSU; the methylation is enhanced by MTERFD/MTERF4。

Antibody type

Mouse monoclonal Antibody

Uniprot ID

SwissProt: Q96CB9 Human

Recombinant

NO

Conjugation

Non-conjugated

Host

Mouse

Isotype

IgG1

Clone

4G3

KO/KD

N/A

Species reactivity

Human

Tested applications

WB, IF-Cell

Predicted species reactivity

N/A

Immunogen

Recombinant protein within human NSUN4 aa 1-384.

Storage

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Form

Liquid

Storage buffer

1*TBS (pH7.4) , 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

2 mg/mL.

Purity

Protein G affinity purified.

Signal pathway

N/A

Recommended dilutions

WB: 1:500-1:1, 000; IF-Cell: 1:50-1:200

Molecular Weight

43 kDa

Subcellular location

Mitochondrion.

Positive control

MCF-7 cell lysates, MCF-7.