AffiAB® Anti-NR3B Antibody
NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. Mediated by glycine. The protein encoded by this gene is a subunit of an N-methyl-D-aspartate (NMDA) receptor. The encoded protein is found primarily in motor neurons, where it forms a heterotetramer with GRIN1 to create an excitatory glycine receptor. Variations in this gene have been proposed to be linked to schizophrenia.
Antibody type
Rabbit polyclonal Antibody
Uniprot ID
SwissProt: O60391 Human
Recombinant
NO
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
N/A
KO/KD
N/A
Species reactivity
Human
Tested applications
WB
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within human NR3B aa 179-220 (Extracellular domain) .
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Immunogen affinity purified.
Signal pathway
cAMP signaling pathway, Neuroscience
Recommended dilutions
WB: 1:500-1:2, 000
Molecular Weight
113 kDa
Subcellular location
Cell membrane, postsynaptic cell membrane.
Positive control
THP-1 cell lysate, 293 cell lysate, Daudi cell lysate.