![AffiAB® Anti-Nogo Antibody [JM02-34]](/web/image/product.product/77216/image_1024/%5BAFG-HB-2723%5D%20AffiAB%C2%AE%20Anti-Nogo%20Antibody%20%5BJM02-34%5D%20?unique=a48b62f)
AffiAB® Anti-Nogo Antibody [JM02-34]
Required to induce the formation and stabilization of endoplasmic reticulum (ER) tubules. They regulate membrane morphogenesis in the ER by promoting tubular ER production.They influence nuclear envelope expansion, nuclear pore complex formation and proper localization of inner nuclear membrane proteins. However each isoform have specific functions mainly depending on their tissue expression specificities (Probable) .
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: Q9NQC3 Human; SwissProt: Q99P72 Mouse
Recombinant
YES
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
JM02-34
KO/KD
N/A
Species reactivity
Human, Mouse
Tested applications
WB, IF-Cell, IF-Tissue, IHC-P, IP, FC
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within Human Nogo aa 111-160 / 1192.
Storage
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:500-1:2, 000; IF-Cell: 1:50-1:200; IF-Tissue: 1:50-1:200; IHC-P: 1:50-1:200; FC: 1:50-1:100; IP: 1:10-1:50
Molecular Weight
Predicted band size: 130 kDa
Subcellular location
Endoplasmic reticulum membrane.
Positive control
Hela cell lysates, mouse skeletal muscle tissue lysates, A549, HepG2, SH-SY5Y, human breast tissue, human fetal skeletal muscle tissue, mouse testis tissue, mouse brain tissue, Hela.