![AffiAB® Anti-NMI Antibody [JE65-78]](/web/image/product.product/77211/image_1024/%5BAFG-HB-2717%5D%20AffiAB%C2%AE%20Anti-NMI%20Antibody%20%5BJE65-78%5D%20?unique=b83e256)
AffiAB® Anti-NMI Antibody [JE65-78]
N-myc-interactor also known as N-myc and STAT interactor is a protein that in humans is encoded by the NMI gene. NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family) , and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has low expression levels in all human fetal and adult tissues tested except brain and has high expression in cancer cell line-myeloid leukemias.
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: Q13287 Human
Recombinant
YES
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
JE65-78
KO/KD
N/A
Species reactivity
Human
Tested applications
WB, IF-Cell, IHC-P, FC
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within human NMI aa 1-51/307.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:1, 000; IF-Cell: 1:50; IHC-P: 1:400; FC: 1:500-1:1, 000
Molecular Weight
Predicted band size: 35 kDa
Subcellular location
Nucleus, Secreted, Cytoplasm.
Positive control
THP-1 cell lysates, human small intestine tissue, Hela, SiHa.