![AffiAB® Anti-NMDAR2A Antibody [JA31-20]](/web/image/product.product/77209/image_1024/%5BAFG-HB-2715%5D%20AffiAB%C2%AE%20Anti-NMDAR2A%20Antibody%20%5BJA31-20%5D%20?unique=a48b62f)
AffiAB® Anti-NMDAR2A Antibody [JA31-20]
NMDAR2A is a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning.
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: Q12879 Human; SwissProt: P35436 Mouse; SwissProt: Q00959 Rat
Recombinant
YES
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
JA31-20
KO/KD
N/A
Species reactivity
Human, Mouse, Rat
Tested applications
WB, IHC-P, IF-Tissue
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within Human NMDAR2A aa 1356-1405 / 1464.
Storage
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
Neuroscience, Calcium signaling pathway, Alzheimer disease, cAMP signaling pathway, Amyotrophic lateral sclerosis
Recommended dilutions
WB: 1:500; IHC-P: 1:50-1:100; IF-Tissue: 1:200
Molecular Weight
165 kDa
Subcellular location
Cell membrane, postsynaptic cell membrane, dendritic spine, synapse, Cytoplasmic vesicle membrane.
Positive control
Rat brain tissue lysate, rat brain tissue, rat skin tissue, human brain tissue, mouse small intestine tissue.