![AffiAB® Anti-NFAT2 Antibody [JA81-03]](/web/image/product.product/77175/image_1024/%5BAFG-HB-2682%5D%20AffiAB%C2%AE%20Anti-NFAT2%20Antibody%20%5BJA81-03%5D%20?unique=a48b62f)
AffiAB® Anti-NFAT2 Antibody [JA81-03]
Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 or IL-4 gene transcription. Also controls gene expression in embryonic cardiac cells. Could regulate not only the activation and proliferation but also the differentiation and programmed death of T-lymphocytes as well as lymphoid and non-lymphoid cells. Required for osteoclastogenesis and regulates many genes important for osteoclast differentiation and function.
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: O95644 Human
Recombinant
YES
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
JA81-03
KO/KD
N/A
Species reactivity
Human
Tested applications
WB, IF-Cell, IHC-P, FC
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within Human NFAT2 aa 894-943 / 943.
Storage
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
衰老, cAMP signaling pathway, Immunology & Inflammation, MAPK signaling pathway, cGMP-PKG signaling pathway
Recommended dilutions
WB: 1:500-1:1, 000; IF-Cell: 1:50-1:200; IHC-P: 1:50-1:200; FC: 1:50-1:100
Molecular Weight
101 kDa
Subcellular location
Cytoplasm. Nucleus.
Positive control
K562 cell lysates, MCF-7, 293T, Hela, human thymus tissue, human tonsil tissue, human spleen tissue, human skeletal muscle tissue, Jurkat.