AffiAB® Anti-NCS1 Antibody [JE56-39]
This gene is a member of the neuronal calcium sensor gene family, which encode calcium-binding proteins expressed predominantly in neurons. The protein encoded by this gene regulates G protein-coupled receptor phosphorylation in a calcium-dependent manner and can substitute for calmodulin. The protein is associated with secretory granules and modulates synaptic transmission and synaptic plasticity. Multiple transcript variants encoding different isoforms have been found for this gene.
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: P62166 Human; SwissProt: Q8BNY6 Mouse; SwissProt: P62168 Rat
Recombinant
YES
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
JE56-39
KO/KD
N/A
Species reactivity
Human, Mouse, Rat
Tested applications
WB
Predicted species reactivity
N/A
Immunogen
Recombinant protein within human NCS1 aa 90-190.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
Neuroscience
Recommended dilutions
WB: 1:500-1:2, 000
Molecular Weight
22 kDa
Subcellular location
Cell membrane, Golgi apparatus, postsynaptic density, perinuclear region, Cytoplasm, Membrane.
Positive control
SH-SY5Y cell lysate, rat brain tissue lysate, mouse cerebellum tissue lysate.