AffiAB® Anti-NCOR2/SMRT Antibody
SMRT / NCoR2 (Nuclear receptor corepressor 2, CTG repeat protein 26, SMAP270, Silencing mediator of retinoic acid and thyroid hormone receptor, Thyroid and retinoic-acid-receptor-associated corepressor, TRAC) is a transcriptional corepressor for nuclear receptors. SMRT / NCoR2 has been shown to play a role in regulating immune response, mediating DNA repair, and in neuronal differentiation and cardiac development. SMRT / NCoR2 is part of a large corepressor complex that contains SIN3A/B and histone deacetylases HDAC1 and HDAC2.
Antibody type
Rabbit polyclonal Antibody
Uniprot ID
SwissProt: Q9Y618 Human; SwissProt: Q9WU42 Mouse; SwissProt: D3ZXN9 Rat
Recombinant
NO
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
N/A
KO/KD
N/A
Species reactivity
Mouse, Rat
Tested applications
WB, FC
Predicted species reactivity
Human
Immunogen
Recombinant protein within N-terminal human NCOR2.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Immunogen affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:1, 000
; FC: 1:500-1:1, 000
Molecular Weight
Predicted band size: 274 kDa
Subcellular location
Nucleus.
Positive control
Mouse brain tissue lysate, rat brain tissue lysate, MG-63.