AffiAB® Anti-Myosin Light Chain 2 Antibody [SN67-09]

Myosin regulatory light chain 2, ventricular/cardiac muscle isoform (MLC-2) also known as the regulatory light chain of myosin (RLC) is a protein that in humans is encoded by the MYL2 gene. This cardiac ventricular RLC isoform is distinct from that expressed in skeletal muscle (MYLPF) , smooth muscle (MYL12B) and cardiac atrial muscle (MYL7) . Ventricular myosin light chain-2 (MLC-2v) refers to the ventricular cardiac muscle form of myosin light chain 2 (Myl2) . MLC-2v is a 19-KDa protein composed of 166 amino acids, that belongs to the EF-hand Ca2+ binding superfamily. [8] MLC-2v interacts with the neck/tail region of the muscle thick filament protein myosin to regulate myosin motility and function.