AffiAB® Anti-MYO19 Antibody [JE64-30]
Myo19 encodes a novel metazoan myosin. Myo19 is expressed in multiple tissues and cell lines. Myo19 localizes to mitochondria. Expressing GFP-Myo19 alters mitochondrial dynamics. Myo19 is a novel mitochondrial associated myosin that is likely to function in actin-based mitochondrial dynamics. Actin-based motor molecule with ATPase activity that localizes to the mitochondrion outer membrane. Motor protein that moves towards the plus-end of actin filaments (By similarity) . Required for mitochondrial inheritance during mitosis. May be involved in mitochondrial transport or positioning.
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: Q96H55 Human
Recombinant
YES
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
JE64-30
KO/KD
N/A
Species reactivity
Human
Tested applications
WB, IF-Cell
Predicted species reactivity
N/A
Immunogen
Recombinant protein within human MYO19 aa 431-680/970.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:500; IF-Cell: 1:50
Molecular Weight
Predicted band size: 109 kDa
Subcellular location
Cytoskeleton, Mitochondrion outer membrane.
Positive control
HeLa cell lysate, A549 cell lysate, K562 cell lysate, NCI-H441.