![AffiAB® Anti-MYBBP1A Antibody [JB40-09]](/web/image/product.product/77076/image_1024/%5BAFG-HB-2574%5D%20AffiAB%C2%AE%20Anti-MYBBP1A%20Antibody%20%5BJB40-09%5D%20?unique=a48b62f)
AffiAB® Anti-MYBBP1A Antibody [JB40-09]
May activate or repress transcription via interactions with sequence specific DNA-binding proteins. Repression may be mediated at least in part by histone deacetylase activity (HDAC activity) . Acts as a corepressor and in concert with CRY1, represses the transcription of the core circadian clock component PER2. Preferentially binds to dimethylated histone H3 'Lys-9' (H3K9me2) on the PER2 promoter.
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: Q9BQG0 Human
Recombinant
YES
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
JB40-09
KO/KD
N/A
Species reactivity
Human
Tested applications
WB, FC, IHC-P, IF-Cell
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within Human MYBBP1A aa 1, 051-1, 100 / 1, 328.
Storage
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:500; FC: 1:50-1:10; IHC-P: 1:50; IF-Cell: 1:10-1:50
Molecular Weight
Predicted band size: 149 kDa
Subcellular location
Cytoplasm. Nucleus.
Positive control
A549 cell lysate, 293T.