AffiAB® Anti-MuERVL-Gag Antibody

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CAT# AFG-HB-2564
Size: 100 μL

433.50 433.5 USD 433.50

433.50

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AffiAB® Anti-MuERVL-Gag Antibody

A large number of retrotransposons are expressed when the zygotic genome is first transcribed, including the endogenous retroviruses (ERVs) , LINE-1 elements, and the non-autonomous SINE elements. At the 2C stage, MuERV-L/MERVL retrovirus-like elements are transiently de-repressed and produce 3% of the transcribed mRNAs. Following the 2C stage, MERVL-retroelement expression is silenced. The newly study discovered that this regulated pattern of MERVL expression overlapped with greater than one hundred 2C-specific genes that have co-opted regulatory elements from these foreign retroviruses to initiate their transcription.

Antibody type

Rabbit polyclonal Antibody

Uniprot ID

SwissProt: V9H130 Mouse

Recombinant

NO

Conjugation

Non-conjugated

Host

Rabbit

Isotype

IgG

Clone

N/A

KO/KD

N/A

Species reactivity

Mouse

Tested applications

IF-Cell

Predicted species reactivity

N/A

Immunogen

Synthetic peptide within human MuERVL-Gag aa 541-581/581.

Storage

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Form

Liquid

Storage buffer

1*PBS (pH7.4) , 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1 mg/mL.

Purity

Immunogen affinity purified.

Signal pathway

N/A

Recommended dilutions

IF-Cell: 1:200

Molecular Weight

67 kDa

Subcellular location

N/A

Positive control

Mouse embryo.