![AffiAB® Anti-MSY2 Antibody [A2-B9-G6]](/web/image/product.product/77047/image_1024/%5BAFG-HB-2541%5D%20AffiAB%C2%AE%20Anti-MSY2%20Antibody%20%5BA2-B9-G6%5D%20?unique=8544d55)
AffiAB® Anti-MSY2 Antibody [A2-B9-G6]
Major constituent of messenger ribonucleoprotein particles (mRNPs) . Involved in the regulation of the stability and/or translation of germ cell mRNAs. Binds to Y-box consensus promoter element. Binds to full-length mRNA with high affinity in a sequence-independent manner. Binds to short RNA sequences containing the consensus site 5'-UCCAUCA-3' with low affinity and limited sequence specificity. Its binding with maternal mRNAs is necessary for its cytoplasmic retention. May mark specific mRNAs (those transcribed from Y-box promoters) in the nucleus for cytoplasmic storage, thereby linking transcription and mRNA storage/translational delay.
Antibody type
Mouse monoclonal Antibody
Uniprot ID
SwissProt: Q9Y2T7 Human; SwissProt: P62960 Mouse; SwissProt: P62961 Rat
Recombinant
NO
Conjugation
Non-conjugated
Host
Mouse
Isotype
IgG1
Clone
A2-B9-G6
KO/KD
N/A
Species reactivity
Human, Mouse
Tested applications
WB, IHC-P
Predicted species reactivity
Rat
Immunogen
Synthetic peptide within Human MSY2 aa 295-344 / 364.
Storage
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*PBS (pH7.4) , 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
2 mg/mL.
Purity
Protein G affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:500-1:2, 000
; IHC-P: 1:50-1:200
Molecular Weight
Predicted band size: 39 kDa
Subcellular location
Cytoplasm, Nucleus.
Positive control
MCF-7 cell lysate, mouse testis tissue lysate.