AffiAB® Anti-Mitoferrin1 Antibody

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CAT# AFG-HB-2482
Size: 100 μL

433.50 433.5 USD 433.50

433.50

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AffiAB® Anti-Mitoferrin1 Antibody

SLC25A37 is a solute carrier localized in the mitochondrial inner membrane. It functions as an essential iron importer for the synthesis of mitochondrial heme and iron-sulfur clusters (summary by Chen et al., 2009) . Mitochondrial iron transporter that specifically mediates iron uptake in developing erythroid cells, thereby playing an essential role in heme biosynthesis. The iron delivered into the mitochondria, presumably as Fe (2+) , is then probably delivered to ferrochelatase to catalyze Fe (2+) incorporation into protoprophyrin IX to make heme (By similarity) .

Antibody type

Rabbit polyclonal Antibody

Uniprot ID

SwissProt: Q9NYZ2 Human; SwissProt: Q920G8 Mouse

Recombinant

NO

Conjugation

Non-conjugated

Host

Rabbit

Isotype

IgG

Clone

N/A

KO/KD

N/A

Species reactivity

Human, Mouse

Tested applications

WB, IF-Cell, IHC-P

Predicted species reactivity

N/A

Immunogen

Synthetic peptide within human Mitoferrin1 aa 289-338.

Storage

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Form

Liquid

Storage buffer

PBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1 mg/mL.

Purity

Immunogen affinity purified.

Signal pathway

N/A

Recommended dilutions

WB: 1:500; IF-Cell: 1:50; IHC-P: 1:400

Molecular Weight

Predicted band size: 37 kDa

Subcellular location

Mitochondrion inner membrane.

Positive control

Mouse spleen tissue lysates, mouse brain tissue lysate, THP-1 cell lysate, Hela, mouse brain tissue.