AffiAB® Anti-MGST1 Antibody
The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, two of which are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. Other family members, demonstrating glutathione S-transferase and peroxidase activities, are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. This gene encodes a protein that catalyzes the conjugation of glutathione to electrophiles and the reduction of lipid hydroperoxides. This protein is localized to the endoplasmic reticulum and outer mitochondrial membrane where it is thought to protect these membranes from oxidative stress. Several transcript variants, some non-protein coding and some protein coding, have been found for this gene.
Antibody type
Rabbit polyclonal Antibody
Uniprot ID
SwissProt: P10620 Human; SwissProt: Q91VS7 Mouse; SwissProt: P08011 Rat
Recombinant
NO
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
N/A
KO/KD
N/A
Species reactivity
Human, Mouse, Rat
Tested applications
WB, IHC-P, IF-Cell, FC
Predicted species reactivity
N/A
Immunogen
Recombinant protein within Human MGST1 aa 1-144 / 155.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*PBS (pH7.4) , 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/ml.
Purity
Immunogen affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:500-1:2000; IHC-P: 1:50-1:200; IF-Cell: 1:50-1:200; FC: 1:50-1:200
Molecular Weight
Predicted band size 10/18 kDa.
Subcellular location
Endoplasmic reticulum, Mitochondrion.
Positive control
Siha cell lysate, HepG2 cell lysate, A549 cell lysate, mouse stomach tissue lysate, HepG2, siha, Rat Adrenal gland tissue, Human liver cancer tissue.