![AffiAB® Anti-mGluR1 Antibody [JM11-61]](/web/image/product.product/76973/image_1024/%5BAFG-HB-2464%5D%20AffiAB%C2%AE%20Anti-mGluR1%20Antibody%20%5BJM11-61%5D%20?unique=a48b62f)
AffiAB® Anti-mGluR1 Antibody [JM11-61]
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system. May participate in the central action of glutamate in the CNS, such as long-term potentiation in the hippocampus and long-term depression in the cerebellum.
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: Q13255 Human; SwissProt: P97772 Mouse; SwissProt: P23385 Rat
Recombinant
YES
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
JM11-61
KO/KD
N/A
Species reactivity
Human, Mouse, Rat
Tested applications
WB, IHC-P
Predicted species reactivity
N/A
Immunogen
Recombinant protein within Human mGluR1 aa 280-420 / 1194.
Storage
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:500-1:1, 000
; IHC-P: 1:50-1:1, 000
Molecular Weight
Predicted band size: 132 kDa
Subcellular location
Cell membrane.
Positive control
rat brain cells lysates, mouse brain tissue, mouse kidney tissue, rat cerebellum tissue, mouse cerebellum tissue.