![AffiAB® Anti-METTL3 Antibody [JE58-20]](/web/image/product.product/76970/image_1024/%5BAFG-HB-2460%5D%20AffiAB%C2%AE%20Anti-METTL3%20Antibody%20%5BJE58-20%5D%20?unique=b83e256)
AffiAB® Anti-METTL3 Antibody [JE58-20]
This gene encodes the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine.
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: Q86U44 Human; SwissProt: Q8C3P7 Mouse
Recombinant
YES
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
JE58-20
KO/KD
N/A
Species reactivity
Human, Mouse
Tested applications
WB, IHC-P, FC
Predicted species reactivity
Rat
Immunogen
Recombinant protein within human METTL3 aa 1-300.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:500-1:1, 000
; IHC-P: 1:50-1:100
; FC: 1:50-1:100
Molecular Weight
64 kDa
Subcellular location
Nucleus, Nucleus speckle, Cytoplasm.
Positive control
HepG2 cell lysate, PC-3 cell lysate, mouse brain tissue, HepG2.