AffiAB® Anti-MEOX2 Antibody
Mesodermal transcription factor that plays a key role in somitogenesis and is required for sclerotome development (By similarity) . Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner (PubMed:22206000) . May have a regulatory role when quiescent vascular smooth muscle cells reenter the cell cycle.
Antibody type
Rabbit polyclonal Antibody
Uniprot ID
SwissProt: P50222 Human; SwissProt: P39020 Rat
Recombinant
NO
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
N/A
KO/KD
N/A
Species reactivity
Rat
Tested applications
WB, IHC-P
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within human MEOX2 aa 255-304/304.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Immunogen affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:500; IHC-P: 1:100-1:500
Molecular Weight
34 kDa
Subcellular location
Nucleus.
Positive control
Rat kidney tissue lysates, rat kidney tissue.