AffiAB® Anti-MEIS1 Antibody [JA13-26]
Acts as a transcriptional regulator of PAX6. Acts as a transcriptional activator of PF4 in complex with PBX1 or PBX2. Required for hematopoiesis, megakaryocyte lineage development and vascular patterning. May function as a cofactor for HOXA7 and HOXA9 in the induction of myeloid leukemias.
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: O00470 Human; SwissProt: Q60954 Mouse
Recombinant
YES
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
JA13-26
KO/KD
N/A
Species reactivity
Human, Mouse, Rat
Tested applications
WB, IP, FC
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within Human MEIS1 aa 328-377 / 390.
Storage
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:500-1:2, 000
; FC: 1:50-1:100
Molecular Weight
47 kDa
Subcellular location
Nucleus.
Positive control
Human skeletal muscle tissue lysate, mouse brain tissue lysate, K562.