![AffiAB® Anti-MC-2 Antibody [JE61-09]](/web/image/product.product/76921/image_1024/%5BAFG-HB-2411%5D%20AffiAB%C2%AE%20Anti-MC-2%20Antibody%20%5BJE61-09%5D%20?unique=b83e256)
AffiAB® Anti-MC-2 Antibody [JE61-09]
Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins. This gene encodes a member of the seven-pass transmembrane G protein-coupled melanocortin receptor protein family that stimulate cAMP signal transduction. The encoded protein is a receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone and is suggested to play a role in sebum generation.
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: P33032 Human; SwissProt: P41149 Mouse
Recombinant
YES
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
JE61-09
KO/KD
N/A
Species reactivity
Human, Mouse
Tested applications
WB, IHC-P
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within human MC-2 aa 1-50/325.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:500-1:2, 000
; IHC-P: 1:50-1:200
Molecular Weight
37 kDa
Subcellular location
Cell membrane.
Positive control
SiHa cell lysates, mouse testis tissue.