AffiAB® Anti-MAD4 Antibody
This gene is a member of the MAD gene family . The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues.
Antibody type
Rabbit polyclonal Antibody
Uniprot ID
SwissProt: Q14582 Human; SwissProt: Q60948 Mouse
Recombinant
NO
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
N/A
KO/KD
N/A
Species reactivity
Mouse, Human
Tested applications
WB
Predicted species reactivity
N/A
Immunogen
Recombinant protein within human MAD4 aa 1-180.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Immunogen affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:1, 000-1:2, 000
Molecular Weight
24 kDa
Subcellular location
Nucleus.
Positive control
Mouse brain tissue lysate, mouse lung tissue lysate.