AffiAB® Anti-LT-alpha Antibody
Lymphotoxin-alpha (LTA) , a member of the tumor necrosis factor (TNF) family of cytokines, was initially isolated on the basis of an anti-tumor activity. LTA plays a key role in communication between lymphocytes and stromal cells, thereby eliciting cytotoxic effects on cancer cells. It induces the expression of vascular cell-adhesion molecule 1 (VCAM1) on vascular endothelial cells and recruits natural killer (NK) cells to parenchymal organs and tumor lesions.
Antibody type
Rabbit polyclonal Antibody
Uniprot ID
SwissProt: P01374 Human
Recombinant
NO
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
N/A
KO/KD
N/A
Species reactivity
Human, Rat
Tested applications
WB
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within Human LT-alpha aa 55-104 / 205.
Storage
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*PBS (pH7.4) , 0.2% BSA, 25% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Immunogen affinity purified.
Signal pathway
细胞因子, NF-KB signaling pathway
Recommended dilutions
WB: 1:1, 000
Molecular Weight
18 kDa
Subcellular location
secretory protein
Positive control
Recombinant LT-alpha (TNF-β)