AffiAB® Anti-LMO2 Antibody
LIM domain only 2 (rhombotin-like 1) , also known as LMO2, RBTNL1, RBTN2, RHOM2, LIM Domain Only Protein 2, TTG2, and T-Cell Translocation Protein 2, is a protein which in humans is encoded by the LMO2 gene. LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc) , where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms.
Antibody type
Rabbit polyclonal Antibody
Uniprot ID
SwissProt: P25791 Human; SwissProt: P25801 Mouse; Entrez Gene: 362176 Rat
Recombinant
NO
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
N/A
KO/KD
N/A
Species reactivity
Human, Mouse, Rat
Tested applications
WB, IF-Cell, IHC-P, FC
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within human LMO2 aa 1-50.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Immunogen affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:500-1:1, 000; IF-Cell:1:50-1:100; IHC-P:1:50-1:200; FC:1:50-1:100
Molecular Weight
18 kDa
Subcellular location
Nucleus.
Positive control
Daudi cell lysates, EA.hy926, RAW264.7, SW620, rat womb tissue, human tonsil tissue, human bone marrow tissue, human womb tissue, mouse brain tissue.