![AffiAB® Anti-LMNB2 Antibody [D5-C2]](/web/image/product.product/76838/image_1024/%5BAFG-HB-2325%5D%20AffiAB%C2%AE%20Anti-LMNB2%20Antibody%20%5BD5-C2%5D%20?unique=315d7a9)
AffiAB® Anti-LMNB2 Antibody [D5-C2]
Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. B-type lamins undergo a series of modifications, such as farnesylation and phosphorylation. Increased phosphorylation of the lamins occurs before envelope disintegration and probably plays a role in regulating lamin associations.
Antibody type
Mouse monoclonal Antibody
Uniprot ID
SwissProt: Q03252 Human; SwissProt: Q62733 Rat; SwissProt: P21619 Mouse; SwissProt: B3DFN3 Zebrafish
Recombinant
NO
Conjugation
Non-conjugated
Host
Mouse
Isotype
IgG2b
Clone
D5-C2
KO/KD
N/A
Species reactivity
Human, Mouse, Rat, Zebrafish
Tested applications
WB, IF-Cell, IHC-P
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within Human LMNB2 aa 571-620 / 620.
Storage
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*PBS (pH7.4) , 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
2 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
Apotosis
Recommended dilutions
WB: 1:1, 000-1:2, 000; IF-Cell: 1:200-1:500; IHC-P:1:500-1:1000
Molecular Weight
Predicted band size: 70 kDa
Subcellular location
Nucleus inner membrane
Positive control
Jurkat cell lysates, hybrid fish (crucian-carp) brain tissue lysates, human uterine tissue.