![AffiAB® Anti-Lipin 1 Antibody [JG37-69]](/web/image/product.product/76831/image_1024/%5BAFG-HB-2317%5D%20AffiAB%C2%AE%20Anti-Lipin%201%20Antibody%20%5BJG37-69%5D%20?unique=a48b62f)
AffiAB® Anti-Lipin 1 Antibody [JG37-69]
Plays important roles in controlling the metabolism of fatty acids at different levels. Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis in the reticulum endoplasmic membrane. Acts also as a nuclear transcriptional coactivator for PPARGC1A/PPARA to modulate lipid metabolism gene expression (By similarity) . Is involved in adipocyte differentiation. May also be involved in mitochondrial fission by converting phosphatidic acid to diacylglycerol (By similarity) .
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: Q14693 Human
Recombinant
YES
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
JG37-69
KO/KD
N/A
Species reactivity
Human
Tested applications
WB, IF-Cell, IF-Tissue, IHC-P, FC, IP
Predicted species reactivity
N/A
Immunogen
Recombinant protein within Human Lipin 1 aa 81-220 / 890.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
Cardiovascular
Recommended dilutions
WB: 1:500-1:1, 000; IF-Cell: 1:50-1:200; IHC-P: 1:50-1:200; FC: 1:50-1:100
Molecular Weight
98 kDa
Subcellular location
Nucleus. Cytoplasm. Endoplasmic reticulum.
Positive control
HUVEC, PC-3M, human liver carcinoma tissue, human colon tissue, human skeletal muscle tissue.