AffiAB® Anti-LASS2 Antibody [B3-2]
The LAG1 gene encodes a protein that has sequence similarity to yeast longevity assurance gene 1. Mutation or overexpression of the related gene in yeast has been shown to alter yeast lifespan. Expression of LASS2 in hepatocellular carcinoma cell lines suppresses the growth of cancer cells.The human protein may play a role in the regulation of cell growth. Alternatively spliced transcript variants encoding the same protein have been described.
Antibody type
Mouse monoclonal Antibody
Uniprot ID
SwissProt: Q96G23 Human; SwissProt: Q90YY7 Zebrafish
Recombinant
NO
Conjugation
Non-conjugated
Host
Mouse
Isotype
IgG2b
Clone
B3-2
KO/KD
N/A
Species reactivity
Human, Zebrafish
Tested applications
WB, IF-Cell, IHC-P
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within Human LASS2 aa 331-380 / 380.
Storage
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*PBS (pH7.4) , 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
2 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:500~1:1, 000; IF-Cell: 1:50~1:200; IHC-P: 1:50~1:200
Molecular Weight
Predicted band size: 45 kDa
Subcellular location
Endoplasmic reticulum membrane
Positive control
K562-AO2 cell lysates, hybrid fish (crucian-carp) brain tissue lysates, human brain tissue, HepG2 cells.