AffiAB® Anti-KLF4 Antibody
KLF4 is a member of the erythroid Kruppel-like factor (EKLF) multigene family that is highly expressed in the differentiating layers of the epidermis. KLF4 plays a critical role in the differentiation of epithelial cells and is essential for normal gastric homeostasis. It regulates the expression of key transcription factors during embryonic development. KLF4 plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. It is required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface.
Antibody type
Rabbit polyclonal Antibody
Uniprot ID
SwissProt: O43474 Human; SwissProt: Q60793 Mouse
Recombinant
NO
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
N/A
KO/KD
N/A
Species reactivity
Human, Mouse
Tested applications
WB, IHC-P, FC
Predicted species reactivity
Rat
Immunogen
Synthetic peptide within human KLF4 aa 406-458.
Storage
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*PBS (pH7.4) , 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Immunogen affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:500; IHC-P:1:200-1:1, 500; FC: 1:100
Molecular Weight
Predicted band size: 55 kDa
Subcellular location
Nucleus.
Positive control
293 cell lysate, F9 cell lysate, human colon tissue.