![AffiAB® Anti-Keratin 12/K12 Antibody [JE55-35]](/web/image/product.product/76746/image_1024/%5BAFG-HB-2226%5D%20AffiAB%C2%AE%20Anti-Keratin%2012-K12%20Antibody%20%5BJE55-35%5D%20?unique=a48b62f)
AffiAB® Anti-Keratin 12/K12 Antibody [JE55-35]
KRT12 encodes the type I intermediate filament chain keratin 12, expressed in corneal epithelia. Mutations in this gene lead to Meesmann corneal dystrophy. May play a unique role in maintaining the normal corneal epithelial function. Together with KRT3, essential for the maintenance of corneal epithelium integrity (By similarity) .
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: Q99456 Human; SwissProt: Q64291 Mouse; SwissProt: Q6IFW5 Rat
Recombinant
YES
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
JE55-35
KO/KD
N/A
Species reactivity
Human, Mouse, Rat
Tested applications
WB, IHC-P
Predicted species reactivity
N/A
Immunogen
Recombinant protein within C-terminal Human Keratin 12/K12.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:500-1:1, 000
; IHC-P: 1:50-1:200
Molecular Weight
54 kDa
Subcellular location
Intermediate filament, cytosol, extracellular exosome.
Positive control
Mouse eyeball tissue lysates, rat eyeball tissue.