![AffiAB® Anti-IQGAP2 Antibody [JE64-54]](/web/image/product.product/74915/image_1024/%5BAFG-HB-2146%5D%20AffiAB%C2%AE%20Anti-IQGAP2%20Antibody%20%5BJE64-54%5D%20?unique=b83e256)
AffiAB® Anti-IQGAP2 Antibody [JE64-54]
This gene encodes a member of the IQGAP family. The encoded protein contains three IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. This protein interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. It also acts as a tumor suppressor and has been found to play a role in regulating innate antiviral responses. Alternative splicing results in multiple transcript variants.
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: Q13576 Human
Recombinant
YES
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
JE64-54
KO/KD
N/A
Species reactivity
Human
Tested applications
WB, IHC-P
Predicted species reactivity
N/A
Immunogen
Recombinant protein within human IQGAP2 aa 1, 301-1, 500/1, 575.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:500
; IHC-P: 1:100
Molecular Weight
Predicted band size: 181 kDa
Subcellular location
Actin cytoskeleton, microtubule, cytosol, extracellular exosome, plasma membrane, cell surface, cytoplasm, filopodium, lamellipodium, microvillus, secretory granule membrane
Positive control
Human placenta tissue lysates, human gallbladder tissue, human prostate tissue.