AffiAB® Anti-Insulin B Chain Antibody

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CAT# AFG-HB-2112
Size: 100 μL

433.50 433.5 USD 433.50

433.50

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AffiAB® Anti-Insulin B Chain Antibody

Insulin is a hormone with extensive effects on both metabolism and several other body systems. It causes most of the body's cells to take up glucose from the blood (including liver, muscle, and fat tissue cells) , storing it as glycogen in the liver and muscle, and stops use of fat as an energy source. Insulin is synthesized as a precursor molecule, proinsulin, which is processed prior to its secretion. A- and B-peptides are joined together by a disulfide bond to form insulin, while the central portion of the precursor molecule is cleaved and released as the C-peptide.

Antibody type

Rabbit polyclonal Antibody

Uniprot ID

SwissProt: P01308 Human; SwissProt: P01325 Mouse; SwissProt: P01322 Rat

Recombinant

NO

Conjugation

Non-conjugated

Host

Rabbit

Isotype

IgG

Clone

N/A

KO/KD

N/A

Species reactivity

Human, Rat, Mouse

Tested applications

IHC-P, FC, ELISA

Predicted species reactivity

N/A

Immunogen

Full length human Insulin B Chain protein.

Storage

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Form

Liquid

Storage buffer

1*PBS (pH7.4) , 0.2% BSA, 25% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1 mg/mL.

Purity

Immunogen affinity purified.

Signal pathway

HIF-1 signaling pathway, PI3K-AKT, cGMP-PKG signaling pathway, Type II diabetes mellitus, Immunology & Inflammation, Autophagy Alzheimer disease, AMPK signaling pathway

Recommended dilutions

IHC-P: 1:200-1:10, 000 ; FC: 1:50-1:100 ; ELISA: 1:5000

Molecular Weight

Predicted band size: 12 kDa

Subcellular location

Secreted.

Positive control

Rat pancreas tissue, human pancreas tissue, HepG2, mouse pancreas tissue.