AffiAB® Anti-IL-6 Antibody [3-A4]
Interleukin 6 (IL-6) is a potent pleiotropic cytokine that regulates cell growth and differentiation of various tissues, and is known particularly for its role in the immune response and acute phase reactions. IL-6 is a cytokine with a wide variety of biological functions and belongs to the?IL-6 superfamily. IL-6 is a potent inducer of the acute phase response and plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. This antibody can recognize mouse interleukin 6, which is a matched antibody-pair with product cat # M1303-1.
Antibody type
Mouse monoclonal Antibody
Uniprot ID
SwissProt: P08505 Mouse
Recombinant
NO
Conjugation
Non-conjugated
Host
Mouse
Isotype
IgG2b
Clone
3-A4
KO/KD
N/A
Species reactivity
Human
Tested applications
WB, IF-Cell, FC, ELISA
Predicted species reactivity
N/A
Immunogen
Recombinant protein within Mouse IL-6 aa 1-211 / 211.
Storage
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*PBS (pH7.4) , 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
2 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:10, 000; ELISA:1:1, 000-1:10, 000; FC:1:1, 000; IF-Cell: 1:50-1:200
Molecular Weight
Predicted band size: 24 kDa
Subcellular location
Secreted.
Positive control
Bioactive mouse IL-6 protein.