AffiAB® Anti-IL-5 Antibody
Interleukin 5 (IL5) is an interleukin produced by type-2 T helper cells and mast cells.Through binding to the interleukin-5 receptor, interleukin 5 stimulates B cell growth and increases immunoglobulin secretion - primarily IgA. It is also a key mediator in eosinophil activation.IL-5 is a 115-amino acid (in human, 133 in the mouse) -long TH2 cytokine that is part of the hematopoietic family. Unlike other members of this cytokine family (namely interleukin 3 and GM-CSF) , this glycoprotein in its active form is a homodimer.
Antibody type
Rabbit polyclonal Antibody
Uniprot ID
SwissProt: P05113 Human
Recombinant
NO
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
N/A
KO/KD
N/A
Species reactivity
Human
Tested applications
WB, IF-Cell, ELISA
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within human IL-5 aa 60-110.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Immunogen affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:500-1:1, 000; IF-Cell: 1:50-1:200; ELISA: 1:5, 000-1:10, 000
Molecular Weight
15 kDa
Subcellular location
Secreted.
Positive control
LOVO cell lysates, LOVO cells.