![AffiAB® Anti-IL-31 Antibody [B7-B0]](/web/image/product.product/74845/image_1024/%5BAFG-HB-2065%5D%20AffiAB%C2%AE%20Anti-IL-31%20Antibody%20%5BB7-B0%5D%20?unique=315d7a9)
AffiAB® Anti-IL-31 Antibody [B7-B0]
Interleukin 31 (IL-31) is a secreted, T-cell-derived, short-chain member of the alpha-helical family of cytokines. The mature region is 141 amino acids (aa) in length and exhibits four alpha-helices. Human and mouse IL-31 are highly divergent at 24% aa sequence identity. The receptor for IL-31 is found on keratinocytes and monocytes. It is a heterodimer composed of the Oncostatin M receptor and a novel gp130-related molecule. IL-31 may be involved in pruritis, or skin itching.
Antibody type
Mouse monoclonal Antibody
Uniprot ID
SwissProt: Q6EBC2 Human
Recombinant
NO
Conjugation
Non-conjugated
Host
Mouse
Isotype
IgG2a
Clone
B7-B0
KO/KD
N/A
Species reactivity
Human
Tested applications
WB, ELISA
Predicted species reactivity
N/A
Immunogen
Recombinant protein within Human Interleukin 31 aa 1-164 / 164.
Storage
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*PBS (pH7.4) , 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
2 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
Immunology & Inflammation, 细胞因子
Recommended dilutions
WB: 1:2, 000
; ELISA: 1:5, 000-1:10, 000
Molecular Weight
Predicted band size: 18 kDa
Subcellular location
Secreted.
Positive control
Bioactive recombinant human IL-31 protein.