AffiAB® Anti-IL-19 Antibody
Interleukin 19 (IL-19) is an immunosuppressive protein that belongs to the IL-10 cytokine subfamily. IL-19 is associated with broad functions across inflammation, cell development, viral responses, and lipid metabolism. As an immunosuppressive cytokine, IL-19 promotes the Th2 (regulatory) T-cell response which supports an anti-inflammatory lymphocyte phenotype, dampens the Th1 T-cell response and inflammatory cytokine secretion (IFNγ) , increases IL-10 (anti-inflammatory) expression in peripheral blood mononuclear cells (PBMC) , and inhibits the production of immunoglobulin G (IgG) from B cells.
Antibody type
Rabbit polyclonal Antibody
Uniprot ID
SwissProt: Q9UHD0 Human
Recombinant
NO
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
N/A
KO/KD
N/A
Species reactivity
Human
Tested applications
IF-Cell, IHC-P
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within mouse IL19 aa 127-176 / 176.
Storage
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*PBS (pH7.4) , 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Immunogen affinity purified.
Signal pathway
细胞因子
Recommended dilutions
IF-Cell: 1:50-1:200; IHC-P: 1:50-1:100
Molecular Weight
Predicted band size: 20 kDa
Subcellular location
Secreted.
Positive control
Hela, HUVEC, SH-SY5Y, human tonsil tissue, human spleen tissue.