![AffiAB® Anti-IL-10RB Antibody [A8E11]](/web/image/product.product/74813/image_1024/%5BAFG-HB-2035%5D%20AffiAB%C2%AE%20Anti-IL-10RB%20Antibody%20%5BA8E11%5D%20?unique=b83e256)
AffiAB® Anti-IL-10RB Antibody [A8E11]
Interleukin 10 receptor, beta subunit is a subunit for the interleukin-10 receptor. IL10RB is its human gene. IL10RB has also recently been designated CDW210B (cluster of differentiation W210B) . The protein encoded by this gene belongs to the cytokine receptor family. It is an accessory chain essential for the active interleukin 10 receptor complex. Coexpression of this and IL10RA proteins has been shown to be required for IL10-induced signal transduction. This gene and three other interferon receptor genes, IFNAR2, IFNAR1, and IFNGR2, form a class II cytokine receptor gene cluster located in a small region on chromosome 21.
Antibody type
Mouse monoclonal Antibody
Uniprot ID
SwissProt: Q08334 Human
Recombinant
NO
Conjugation
Non-conjugated
Host
Mouse
Isotype
IgG2a
Clone
A8E11
KO/KD
N/A
Species reactivity
Human
Tested applications
WB
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within Human IL-10RB aa 181-230 / 325.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
PBS (pH7.4) , 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
2 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:500-1:1, 000
Molecular Weight
Predicted band size: 37 kDa
Subcellular location
Membrane.
Positive control
Jurkat cell lysate, 293T cell lysate, U87MG cell lysates.