AffiAB® Anti-IFNAR2 Antibody
The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. Multiple transcript variants encoding at least two different isoforms have been found for this gene.
Antibody type
Rabbit polyclonal Antibody
Uniprot ID
SwissProt: P48551 Human
Recombinant
NO
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
N/A
KO/KD
N/A
Species reactivity
Human
Tested applications
WB, IHC-P, IF-Cell
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within human IFNAR2 aa 194-243 (Extracellular domain) .
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
PBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Immunogen affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:500; IHC-P: 1:600; IF-Cell: 1:200
Molecular Weight
Predicted band size: 58 kDa
Subcellular location
Cell membrane; Secreted.
Positive control
SK-Br-3 cell lysate, MCF-7 cell lysate, HepG2 cell lysate, human prostate tissue, SH-SY5Y, SiHa.