![AffiAB® Anti-IFNAR1 Antibody [A5-A3]](/web/image/product.product/74776/image_1024/%5BAFG-HB-1997%5D%20AffiAB%C2%AE%20Anti-IFNAR1%20Antibody%20%5BA5-A3%5D%20?unique=d31c23b)
AffiAB® Anti-IFNAR1 Antibody [A5-A3]
Interferon-alpha/beta receptor alpha chain is a protein that in humans is encoded by the IFNAR1 gene.
Antibody type
Mouse monoclonal Antibody
Uniprot ID
SwissProt: P17181 Human; SwissProt: P33896 Mouse
Recombinant
NO
Conjugation
Non-conjugated
Host
Mouse
Isotype
IgG1
Clone
A5-A3
KO/KD
N/A
Species reactivity
Human, Mouse
Tested applications
WB, IHC-P, IF-Cell
Predicted species reactivity
N/A
Immunogen
Recombinant protein within human IFNAR1 aa 28-127 (Extracellular) .
Storage
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*PBS (pH7.4) , 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
2 mg/mL.
Purity
Protein G affinity purified.
Signal pathway
Immunology & Inflammation, JAK-STAT signaling pathway, PI3K-AKT
Recommended dilutions
WB: 1:500; IF-Cell: 1:50-1:200; IHC-P: 1:50-1:200
Molecular Weight
56 kDa
Subcellular location
Endosome. Cell membrane.
Positive control
K562, A431, Siha, mouse brain tissue lysate, NCCIT, SHUG-44, human lung tissue, human skin tissue, human colon tissue.The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for type I interferons, including interferon-alpha, -beta, and -lambda. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The encoded protein also functions as an antiviral factor.