AffiAB® Anti-IFN gamma Receptor beta Antibody
This gene (IFNGR2) encodes the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD) , also known as familial disseminated atypical mycobacterial infection. MSMD is a genetically heterogeneous disease with autosomal recessive, autosomal dominant or X-linked inheritance.
Antibody type
Rabbit polyclonal Antibody
Uniprot ID
SwissProt: P38484 Human; Entrez Gene: 15980 Mouse; Entrez Gene: 360697 Rat
Recombinant
NO
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
N/A
KO/KD
N/A
Species reactivity
Human, Mouse, Rat
Tested applications
WB, IF-Cell, IHC-P
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within human IFN gamma Receptor beta aa 288-337.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
PBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Immunogen affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:500; IF-Cell: 1:200; IHC-P: 1:600
Molecular Weight
Predicted band size: 38 kDa
Subcellular location
Golgi apparatus membrane, Cell membrane, Cytoplasm, Endoplasmic reticulum membrane, Cytoplasmic vesicle membrane.
Positive control
Jurkat cell lysate, Hela cell lysate, A431 cell lysate, human liver tissue lysate, SH-SY5Y, human stomach tissue, mouse bladder tissue, rat lung tissue.