AffiAB® Anti-ICAM-1 Antibody [J0-F7]
This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor.
Antibody type
Mouse monoclonal Antibody
Uniprot ID
SwissProt: P05362 Human
Recombinant
NO
Conjugation
Non-conjugated
Host
Mouse
Isotype
IgG2c
Clone
J0-F7
KO/KD
N/A
Species reactivity
Human
Tested applications
WB, IF-Cell, FC
Predicted species reactivity
N/A
Immunogen
Recombinant protein within human ICAM-1 aa 30-300.
Storage
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*PBS (pH7.4) , 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
2 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
Immunology & Inflammation, Rheumatoid arthritis, Neuroscience, NF-KB signaling pathway
Recommended dilutions
WB:1:500-1:2, 000; IF-Cell:1:50-1:100; FC:1:50-1:100
Molecular Weight
58 kDa
Subcellular location
Membrane.
Positive control
Raji cell lysates, Daudi cell lysates, Hela, HUVEC, Jurkat.