AffiAB® Anti-Human IgG kapa light chain Antibody [A11-G11]
IgG is the most abundant immunoglobulin and is approximately equally distributed in blood and in tissue liquids, constituting 75% of serum immunoglobulins in humans. There are 4 subclasses: IgG1 (66%) , IgG2 (23%) , IgG3 (7%) and IgG4 (4%) . This is the only isotype that can pass through the human placenta, thereby providing protection to the fetus in its first weeks of life before its own immune system has developed. This antibody reacts with kappa-light-chain of human IgG.
Antibody type
Mouse monoclonal Antibody
Uniprot ID
SwissProt: Q6P5S8 Human
Recombinant
NO
Conjugation
Non-conjugated
Host
Mouse
Isotype
IgG2a
Clone
A11-G11
KO/KD
N/A
Species reactivity
Human
Tested applications
WB, ELISA
Predicted species reactivity
N/A
Immunogen
Native protein.
Storage
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*PBS (pH7.4) , 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
2 mg/ml.
Purity
Protein A affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:2, 000-1:5, 000
; ELISA: 1:5, 000
Molecular Weight
25 kDa
Subcellular location
Cell membrane, Immunoglobulin, Membrane, Secreted
Positive control
Human IgG protein lysates.