AffiAB® Anti-HSP90 Beta Antibody [2-1-G3]
Heat shock protein HSP 90-beta also called HSP90beta is a protein that in humans is encoded by the HSP90AB1 gene. HSP90AB1 is a molecular chaperone. Chaperones are proteins that bind to other proteins, thereby stabilizing them in an ATP-dependent manner. Chaperones stabilize new proteins during translation, mature proteins which are partially unstable but also proteins that have become partially denatured due to various kinds of cellular stress. In case proper folding or refolding is impossible, HSPs mediate protein degradation. They also have specialized functions, such as intracellular transport into organelles.
Antibody type
Mouse monoclonal Antibody
Uniprot ID
SwissProt: P08238 Human; SwissProt: P11499 Mouse; SwissProt: P34058 Rat
Recombinant
NO
Conjugation
Non-conjugated
Host
Mouse
Isotype
IgG2a
Clone
2-1-G3
KO/KD
N/A
Species reactivity
Human, Mouse, Rat
Tested applications
WB, IHC-P
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within Human HSP90 Beta aa 311-360 / 724.
Storage
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*PBS (pH7.4) , 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
2 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
PI3K-AKT
Recommended dilutions
WB: 1:5, 000
; IHC-P: 1:100-1:200
Molecular Weight
Predicted band size: 83 kDa
Subcellular location
Cytoplasm
Positive control
Hela, NIH/3T3, PC12, 293T, A431, COS-1, Jurkat, HepG2, A549, Raji, mouse brain tissue, mouse heart tissue, rat brain tissue , rat heart tissue, human colon carcinoma tissue, human tonsil tissue, mouse testis tissue.