AffiAB® Anti-Hsp75 Antibody [SD08-71]
The heat shock proteins (HSPs) comprise a group of highly conserved, abundantly expressed proteins with diverse functions, including the assembly and sequestering of multiprotein complexes, transportation of nascent polypeptide chains across cellular membranes and regulation of protein folding. Heat shock protein 75 mitochondrial precursor (HSP 75) , also called tumor necrosis factor type 1 receptor-associated protein (TRAP1) , is a 704 amino acid member of the heat shock protein 90 family. HSP 75 localizes to the mitochondrion and is expressed in a variety of tissues, including skeletal muscle, liver, heart, brain, pancreas, lung and placenta, functioning as a chaperone that expresses an ATPase activity.
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: Q12931 Human
Recombinant
YES
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
SD08-71
KO/KD
N/A
Species reactivity
Human
Tested applications
WB, IP
Predicted species reactivity
N/A
Immunogen
Recombinant protein within Human Hsp75 aa 560-704 / 704.
Storage
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
Parkinson’s disease
Recommended dilutions
WB: 1:1, 000-1:2, 000
Molecular Weight
75 kDa
Subcellular location
Mitochondrion, Mitochondrion inner membrane, Mitochondrion matrix.
Positive control
Hela cell lysate, 293T cell lysate.