![AffiAB® Anti-Hsp22 Antibody [JJ08-53]](/web/image/product.product/74721/image_1024/%5BAFG-HB-1940%5D%20AffiAB%C2%AE%20Anti-Hsp22%20Antibody%20%5BJJ08-53%5D%20?unique=d31c23b)
AffiAB® Anti-Hsp22 Antibody [JJ08-53]
Heat shock protein beta-8 is a protein that in humans is encoded by the HSPB8 gene. Mutations in this gene have been associated with an autosomal dominant rimmed vacuolar myopathy The clinical features of this condition are distal and proximal myopathy. MRI show severe relatively symmetric multifocal fatty degenerative changes within the muscles. Muscle biopsy shows rimmed vacuoles, muscle fiber atrophy and endomysial fibrosis.
Antibody type
Recombinant Rabbit monoclonal Antibody
Uniprot ID
SwissProt: Q9UJY1 Human; SwissProt: Q9JK92 Mouse; SwissProt: Q9EPX0 Rat
Recombinant
YES
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
JJ08-53
KO/KD
N/A
Species reactivity
Human, Mouse, Rat
Tested applications
WB, IF-Cell, IF-Tissue, IHC-P
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within Human Hsp22 aa 1-50 / 196.
Storage
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Protein A affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:500-1:2, 000; IF-Cell: 1:100-1:500; IF-Tissue: 1:100-1:500; IHC-P: 1:50-1:200
Molecular Weight
Predicted band size: 22 kDa
Subcellular location
Nucleus, Cytoplasm.
Positive control
HepG2 cell lysate, mouse skeletal muscle tissue lysate, Hela, A431, SH-SY5Y, mouse brain tissue, rat skeletal muscle tissue.