AffiAB® Anti-HNF-4-alpha Antibody [SN72-03]

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CAT# AFG-HB-1909
Size: 100 μL

496.50 496.5 USD 496.50

496.50

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AffiAB® Anti-HNF-4-alpha Antibody [SN72-03]

HNF-4 alpha is a transcription factor that binds DNA as a homodimer. HNF-4 alpha is important in liver, kidney, and intestinal development. It has also been intensely studied as one of a variety of genes responsible for diabetes mellitus. HNF-4 alpha has been shown in knock out mice to be essential for the morphogenic and functional differentiation of hepatocytes. HNF-4 alpha is a dominant regulator of epithelial phenotypes able to drive the mesenchymal-to-epithelial transition when expressed in fibroblasts.

Antibody type

Recombinant Rabbit monoclonal Antibody

Uniprot ID

SwissProt: P41235 Human

Recombinant

YES

Conjugation

Non-conjugated

Host

Rabbit

Isotype

IgG

Clone

SN72-03

KO/KD

N/A

Species reactivity

Human

Tested applications

WB, IF-Cell, IF-Tissue, IHC-P, FC

Predicted species reactivity

Mouse

Immunogen

Synthetic peptide within Human HNF-4-alpha aa 21-70 / 474.

Storage

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Form

Liquid

Storage buffer

1*TBS (pH7.4) , 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1 mg/mL.

Purity

Protein A affinity purified.

Signal pathway

Cardiovascular, AMPK signaling pathway

Recommended dilutions

WB: 1:500-1:1, 000; IF-Cell: 1:50-1:200; IF-Tissue: 1:50-1:200; IHC-P: 1:100-1:500; FC: 1:50-1:100

Molecular Weight

Predicted band size: 53 kDa

Subcellular location

Nucleus.

Positive control

A549 cell lysates, LOVO cell lysates, SW480, human colon carcinoma tissue, human kidney tissue, human liver carcinoma tissue, human small intestine tissue, HepG2.