AffiAB® Anti-Hemagglutinin-neuraminidase Antibody
Hemagglutinin-neuraminidase refers to a single viral protein that has both hemagglutinin and neuraminidase activity. This is in contrast to the proteins found in influenza, where both functions exist but in two separate proteins. However it does show a structural similarity to influenza viral neuraminidase and has a six-bladed beta-propeller structure. Hemagglutinin-neuraminidase allows the virus to stick to a potential host cell, and cut itself loose if necessary. Hemagglutinin-neuraminidase can be found in a variety of paramyxoviruses including mumps virus, human parainfluenza virus 3, and the avian pathogen Newcastle disease virus.
Antibody type
Rabbit polyclonal Antibody
Uniprot ID
SwissProt: B5UA17 Avian avulavirus 1
Recombinant
NO
Conjugation
Non-conjugated
Host
Rabbit
Isotype
IgG
Clone
N/A
KO/KD
N/A
Species reactivity
Avian avulavirus 1
Tested applications
WB, ELISA
Predicted species reactivity
N/A
Immunogen
Synthetic peptide within newcastle disease virus Hemagglutinin-neuraminidase aa 537-586 / 586.
Storage
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Form
Liquid
Storage buffer
1*PBS (pH7.4) , 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 mg/mL.
Purity
Immunogen affinity purified.
Signal pathway
N/A
Recommended dilutions
WB: 1:500-1, 000; ELISA: 1:5, 000-1:10, 000
Molecular Weight
64 kDa
Subcellular location
Virion membrane.
Positive control
Hemagglutinin-neuraminidase transfected HEK293 cell.